What quality control operations are required for packaging and labeling operations?
21 C.F.R. § 111.127
in effectEffective: 2024-07-01Quality control operations for packaging and labeling operations must include:
(a) Reviewing the results of any visual examination and documentation to ensure that specifications established under § 111.70(f) are met for all products that you receive for packaging and labeling as a dietary supplement (and for distribution rather than for return to the supplier);
(b) Approving, and releasing from quarantine, all products that you receive for packaging or labeling as a dietary supplement (and for distribution rather than for return to the supplier) before they are used for packaging or labeling;
(c) Reviewing and approving all records for packaging and label operations;
(d) Determining whether the finished packaged and labeled dietary supplement conforms to specifications established in accordance with § 111.70(g);
(e) Conducting any required material review and making any required disposition decision;
(f) Approving or rejecting any repackaging of a packaged dietary supplement;
(g) Approving or rejecting any relabeling of a packaged and labeled dietary supplement; and
(h) Approving for release, or rejecting, any packaged and labeled dietary supplement (including a repackaged or relabeled dietary supplement) for distribution.
Source: eCFRURL: https://www.ecfr.gov/api/versioner/v1/full/2024-07-01/title-21.xmlFetched: 7/26/2026