Ceftiofur.
21 C.F.R. § 556.113
in effectEffective: 2024-07-01(a) Acceptable daily intake and acute reference dose—(1) Acceptable daily intake (ADI). The ADI for total residue of ceftiofur is 30 µg/kg of body weight per day.
(2) Acute reference dose (ARfD). The ARfD for total residue of ceftiofur is 0.830 mg/kg of body weight.
(b) Tolerances. The tolerances for desfuroylceftiofur (marker residue) are:
(1) Cattle. (i) Kidney (target tissue): 0.4 ppm.
(ii) Liver: 2 ppm.
(iii) Muscle: 1 ppm.
(iv) Milk: 0.1 ppm.
(2) Chickens and turkeys. Edible tissues (excluding eggs): Not required.
(3) Goats. (i) Kidney (target tissue): 8 ppm.
(ii) Liver: 2 ppm.
(iii) Muscle: 1 ppm.
(iv) Milk: 0.1 ppm.
(4) Sheep. Edible tissues (excluding milk): Not required.
(5) Swine. (i) Kidney (target tissue): 0.25 ppm.
(ii) Liver: 3 ppm.
(iii) Muscle: 2 ppm.
(c) Related conditions of use. See §§ 522.313a, 522.313b, 522.313c, and 526.313 of this chapter.
Source: eCFRURL: https://www.ecfr.gov/api/versioner/v1/full/2024-07-01/title-21.xmlFetched: 7/26/2026